Hitting the Bull’s-Eye in Metastatic Cancers—NSAIDs Elevate ROS in Mitochondria, Inducing Malignant Cell Death

Tumor metastases that impede the function of vital organs are a major cause of cancer related mortality. Mitochondrial oxidative stress induced by hypoxia, low nutrient levels, or other stresses, such as genotoxic events, act as key drivers of the malignant changes in primary tumors to enhance their...

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Detalles Bibliográficos
Autores principales: Ralph, Stephen John, Pritchard, Rhys, Rodríguez-Enríquez, Sara, Moreno-Sánchez, Rafael, Ralph, Raymond Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381202/
https://www.ncbi.nlm.nih.gov/pubmed/25688484
http://dx.doi.org/10.3390/ph8010062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381202/
https://www.ncbi.nlm.nih.gov/pubmed/25688484
http://dx.doi.org/10.3390/ph8010062

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