Normal Distribution of CD8+ T-Cell-Derived ELISPOT Counts within Replicates Justifies the Reliance on Parametric Statistics for Identifying Positive Responses

Accurate assessment of positive ELISPOT responses for low frequencies of antigen-specific T-cells is controversial. In particular, it is still unknown whether ELISPOT counts within replicate wells follow a theoretical distribution function, and thus whether high power parametric statistics can be us...

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Detalles Bibliográficos
Autores principales: Karulin, Alexey Y., Caspell, Richard, Dittrich, Marcus, Lehmann, Paul V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381212/
https://www.ncbi.nlm.nih.gov/pubmed/25738924
http://dx.doi.org/10.3390/cells4010096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381212/
https://www.ncbi.nlm.nih.gov/pubmed/25738924
http://dx.doi.org/10.3390/cells4010096

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