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p53 Acetylation: Regulation and Consequences

Post-translational modifications of p53 are critical in modulating its tumor suppressive functions. Ubiquitylation, for example, plays a major role in dictating p53 stability, subcellular localization and transcriptional vs. non-transcriptional activities. Less is known about p53 acetylation. It has...

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Detalles Bibliográficos
Autores principales: Reed, Sara M., Quelle, Dawn E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381250/
https://www.ncbi.nlm.nih.gov/pubmed/25545885
http://dx.doi.org/10.3390/cancers7010030