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The Roles of Akt Isoforms in the Regulation of Podosome Formation in Fibroblasts and Extracellular Matrix Invasion

Mesenchymal cells employ actin-based membrane protrusions called podosomes and invadopodia for cross-tissue migration during normal human development such as embryogenesis and angiogenesis, and in diseases such as atherosclerosis plaque formation and cancer cell metastasis. The Akt isoforms, downstr...

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Detalles Bibliográficos
Autores principales: Eves, Robert, Oldham, Robyn, Jia, Lilly, Mak, Alan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381253/
https://www.ncbi.nlm.nih.gov/pubmed/25575302
http://dx.doi.org/10.3390/cancers7010096