Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors

Cyclin-dependent kinases (CDK/Cyclins) form a family of heterodimeric kinases that play central roles in regulation of cell cycle progression, transcription and other major biological processes including neuronal differentiation and metabolism. Constitutive or deregulated hyperactivity of these kina...

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Detalles Bibliográficos
Autores principales: Peyressatre, Marion, Prével, Camille, Pellerano, Morgan, Morris, May C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381256/
https://www.ncbi.nlm.nih.gov/pubmed/25625291
http://dx.doi.org/10.3390/cancers7010179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381256/
https://www.ncbi.nlm.nih.gov/pubmed/25625291
http://dx.doi.org/10.3390/cancers7010179

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