Cargando…
Targeting Cyclin-Dependent Kinases in Human Cancers: From Small Molecules to Peptide Inhibitors
Cyclin-dependent kinases (CDK/Cyclins) form a family of heterodimeric kinases that play central roles in regulation of cell cycle progression, transcription and other major biological processes including neuronal differentiation and metabolism. Constitutive or deregulated hyperactivity of these kina...
Autores principales: | Peyressatre, Marion, Prével, Camille, Pellerano, Morgan, Morris, May C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381256/ https://www.ncbi.nlm.nih.gov/pubmed/25625291 http://dx.doi.org/10.3390/cancers7010179 |
Ejemplares similares
-
Fluorescent Peptide Biosensor for Probing the Relative Abundance of Cyclin-Dependent Kinases in Living Cells
por: Kurzawa, Laetitia, et al.
Publicado: (2011) -
Identification of Quinazolinone Analogs Targeting CDK5 Kinase Activity and Glioblastoma Cell Proliferation
por: Peyressatre, Marion, et al.
Publicado: (2020) -
Small molecule inhibitors of cyclin-dependent kinase 9 for cancer therapy
por: Alsfouk, Aisha
Publicado: (2021) -
Stapled peptide targeting the CDK4/Cyclin D interface combined with Abemaciclib inhibits KRAS mutant lung cancer growth
por: Bouclier, Celine, et al.
Publicado: (2020) -
The Renaissance of Cyclin Dependent Kinase Inhibitors
por: Ettl, Tobias, et al.
Publicado: (2022)