Immunreconstitution and Infectious Complications After Rituximab Treatment in Children and Adolescents: What Do We Know and What Can We Learn from Adults?

Rituximab, an anti CD20 monoclonal antibody, is widely used in the treatment of B-cell malignancies in adults and increasingly in pediatric patients. By depleting B-cells, rituximab interferes with humoral immunity. This review provides a comprehensive overview of immune reconstitution and infectiou...

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Detalles Bibliográficos
Autores principales: Worch, Jennifer, Makarova, Olga, Burkhardt, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381260/
https://www.ncbi.nlm.nih.gov/pubmed/25643241
http://dx.doi.org/10.3390/cancers7010305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381260/
https://www.ncbi.nlm.nih.gov/pubmed/25643241
http://dx.doi.org/10.3390/cancers7010305

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