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Stat5 Exerts Distinct, Vital Functions in the Cytoplasm and Nucleus of Bcr-Abl(+) K562 and Jak2(V617F)(+) HEL Leukemia Cells

Signal transducers and activators of transcription (Stats) play central roles in the conversion of extracellular signals, e.g., cytokines, hormones and growth factors, into tissue and cell type specific gene expression patterns. In normal cells, their signaling potential is strictly limited in exten...

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Detalles Bibliográficos
Autores principales: Weber, Axel, Borghouts, Corina, Brendel, Christian, Moriggl, Richard, Delis, Natalia, Brill, Boris, Vafaizadeh, Vida, Groner, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381271/
https://www.ncbi.nlm.nih.gov/pubmed/25809097
http://dx.doi.org/10.3390/cancers7010503