Silencing efficacy prediction: a retrospective study on target mRNA features

Post-transcriptional gene silencing is a widely used method to suppress gene expression. Unfortunately only a portion of siRNAs do successfully reduce gene expression. Target mRNA secondary structures and siRNA-mRNA thermodynamic features are believed to contribute to the silencing activity. However...

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Detalles Bibliográficos
Autores principales: Pascut, Devis, Bedogni, Giorgio, Tiribelli, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381284/
https://www.ncbi.nlm.nih.gov/pubmed/25702798
http://dx.doi.org/10.1042/BSR20140147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381284/
https://www.ncbi.nlm.nih.gov/pubmed/25702798
http://dx.doi.org/10.1042/BSR20140147

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