Treatment of cardiac arrhythmias in a mouse model of Rett syndrome with Na(+)-channel-blocking antiepileptic drugs

One quarter of deaths associated with Rett syndrome (RTT), an X-linked neurodevelopmental disorder, are sudden and unexpected. RTT is associated with prolonged QTc interval (LQT), and LQT-associated cardiac arrhythmias are a potential cause of unexpected death. The standard of care for LQT in RTT is...

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Detalles Bibliográficos
Autores principales: Herrera, José A., Ward, Christopher S., Pitcher, Meagan R., Percy, Alan K., Skinner, Steven, Kaufmann, Walter E., Glaze, Daniel G., Wehrens, Xander H. T., Neul, Jeffrey L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381335/
https://www.ncbi.nlm.nih.gov/pubmed/25713300
http://dx.doi.org/10.1242/dmm.020131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381335/
https://www.ncbi.nlm.nih.gov/pubmed/25713300
http://dx.doi.org/10.1242/dmm.020131

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