Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression

E-cadherin inactivation underpins the progression of invasive lobular breast carcinoma (ILC). In ILC, p120-catenin (p120) translocates to the cytosol where it controls anchorage independence through the Rho-Rock signaling pathway, a key mechanism driving tumor growth and metastasis. We now demonstra...

Descripción completa

Detalles Bibliográficos
Autores principales: van de Ven, Robert A. H., Tenhagen, Milou, Meuleman, Wouter, van Riel, Jeske J. G., Schackmann, Ron C. J., Derksen, Patrick W. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381336/
https://www.ncbi.nlm.nih.gov/pubmed/25713299
http://dx.doi.org/10.1242/dmm.018648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381336/
https://www.ncbi.nlm.nih.gov/pubmed/25713299
http://dx.doi.org/10.1242/dmm.018648

Ejemplares similares