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Nuclear p120-catenin regulates the anoikis resistance of mouse lobular breast cancer cells through Kaiso-dependent Wnt11 expression
E-cadherin inactivation underpins the progression of invasive lobular breast carcinoma (ILC). In ILC, p120-catenin (p120) translocates to the cytosol where it controls anchorage independence through the Rho-Rock signaling pathway, a key mechanism driving tumor growth and metastasis. We now demonstra...
Autores principales: | van de Ven, Robert A. H., Tenhagen, Milou, Meuleman, Wouter, van Riel, Jeske J. G., Schackmann, Ron C. J., Derksen, Patrick W. B. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Limited
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381336/ https://www.ncbi.nlm.nih.gov/pubmed/25713299 http://dx.doi.org/10.1242/dmm.018648 |
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