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The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis

Treatment of non-small cell lung cancer (NSCLC) is based on histological analysis and molecular profiling of targetable driver oncogenes. Therapeutic responses are further defined by the landscape of passenger mutations, or loss of tumor suppressor genes. We report here a thorough study to address t...

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Detalles Bibliográficos
Autores principales: Lahtela, Jenni, Pradhan, Barun, Närhi, Katja, Hemmes, Annabrita, Särkioja, Merja, Kovanen, Panu E., Brown, Arthur, Verschuren, Emmy W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381338/
https://www.ncbi.nlm.nih.gov/pubmed/25713296
http://dx.doi.org/10.1242/dmm.019257