Modeling autosomal recessive cutis laxa type 1C in mice reveals distinct functions for Ltbp-4 isoforms

Recent studies have revealed an important role for LTBP-4 in elastogenesis. Its mutational inactivation in humans causes autosomal recessive cutis laxa type 1C (ARCL1C), which is a severe disorder caused by defects of the elastic fiber network. Although the human gene involved in ARCL1C has been dis...

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Detalles Bibliográficos
Autores principales: Bultmann-Mellin, Insa, Conradi, Anne, Maul, Alexandra C., Dinger, Katharina, Wempe, Frank, Wohl, Alexander P., Imhof, Thomas, Wunderlich, F. Thomas, Bunck, Alexander C., Nakamura, Tomoyuki, Koli, Katri, Bloch, Wilhelm, Ghanem, Alexander, Heinz, Andrea, von Melchner, Harald, Sengle, Gerhard, Sterner-Kock, Anja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Limited 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381339/
https://www.ncbi.nlm.nih.gov/pubmed/25713297
http://dx.doi.org/10.1242/dmm.018960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381339/
https://www.ncbi.nlm.nih.gov/pubmed/25713297
http://dx.doi.org/10.1242/dmm.018960

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