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eIF6 over-expression increases the motility and invasiveness of cancer cells by modulating the expression of a critical subset of membrane-bound proteins

BACKGROUND: Eukaryotic Initiation factor 6 (eIF6) is a peculiar translation initiation factor that binds to the large 60S ribosomal subunits, controlling translation initiation and participating in ribosome biogenesis. In the past, knowledge about the mechanisms adopted by the cells for controlling...

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Detalles Bibliográficos
Autores principales: Pinzaglia, Michela, Montaldo, Claudia, Polinari, Dorina, Simone, Mattei, La Teana, Anna, Tripodi, Marco, Mancone, Carmine, Londei, Paola, Benelli, Dario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381359/
https://www.ncbi.nlm.nih.gov/pubmed/25886394
http://dx.doi.org/10.1186/s12885-015-1106-3