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eIF6 over-expression increases the motility and invasiveness of cancer cells by modulating the expression of a critical subset of membrane-bound proteins
BACKGROUND: Eukaryotic Initiation factor 6 (eIF6) is a peculiar translation initiation factor that binds to the large 60S ribosomal subunits, controlling translation initiation and participating in ribosome biogenesis. In the past, knowledge about the mechanisms adopted by the cells for controlling...
Autores principales: | Pinzaglia, Michela, Montaldo, Claudia, Polinari, Dorina, Simone, Mattei, La Teana, Anna, Tripodi, Marco, Mancone, Carmine, Londei, Paola, Benelli, Dario |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381359/ https://www.ncbi.nlm.nih.gov/pubmed/25886394 http://dx.doi.org/10.1186/s12885-015-1106-3 |
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