The recently identified modifier of murine metastable epialleles, Rearranged L-Myc Fusion, is involved in maintaining epigenetic marks at CpG island shores and enhancers

BACKGROUND: We recently identified a novel protein, Rearranged L-myc fusion (Rlf), that is required for DNA hypomethylation and transcriptional activity at two specific regions of the genome known to be sensitive to epigenetic gene silencing. To identify other loci affected by the absence of Rlf, we...

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Detalles Bibliográficos
Autores principales: Harten, Sarah K, Oey, Harald, Bourke, Lauren M, Bharti, Vandhana, Isbel, Luke, Daxinger, Lucia, Faou, Pierre, Robertson, Neil, Matthews, Jacqueline M, Whitelaw, Emma
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381397/
https://www.ncbi.nlm.nih.gov/pubmed/25857663
http://dx.doi.org/10.1186/s12915-015-0128-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381397/
https://www.ncbi.nlm.nih.gov/pubmed/25857663
http://dx.doi.org/10.1186/s12915-015-0128-2

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