Cargando…

Transcription of RORγt in Developing Th17 Cells is Regulated by E-Proteins

In the present study we investigated the molecular mechanisms regulating the expression of RORγt, the central factor controlling IL-17 transcription and Th17 differentiation. In key studies we found that cells from mice with major deletions of the E-protein transcription factors, E2A and HEB, displa...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Fuping, Fuss, Ivan J., Yang, Zhiqiong, Strober, Warren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381430/
https://www.ncbi.nlm.nih.gov/pubmed/24064669
http://dx.doi.org/10.1038/mi.2013.69