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Transcription of RORγt in Developing Th17 Cells is Regulated by E-Proteins
In the present study we investigated the molecular mechanisms regulating the expression of RORγt, the central factor controlling IL-17 transcription and Th17 differentiation. In key studies we found that cells from mice with major deletions of the E-protein transcription factors, E2A and HEB, displa...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381430/ https://www.ncbi.nlm.nih.gov/pubmed/24064669 http://dx.doi.org/10.1038/mi.2013.69 |