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Genomics driven-oncology: challenges and perspectives

Molecularly defined subgroups of tumors characterized by specific driver mutations have been identified in the majority of cancers. The availability of novel drugs capable of targeting signaling pathways activated by genetic derangements has led to hypothesize the possibility to treat patients based...

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Detalles Bibliográficos
Autores principales: Normanno, Nicola, Cree, Ian A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381449/
https://www.ncbi.nlm.nih.gov/pubmed/25884512
http://dx.doi.org/10.1186/s12885-015-1147-7