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Role for cFMS in maintaining alternative macrophage polarization in SIV infection: implications for HIV neuropathogenesis

BACKGROUND: Macrophage-colony stimulating factor (M-CSF) has been implicated in HIV neuropathogenesis through its ability to modulate activation of macrophages (MΦs) and microglia, as well as enhance the susceptibility of these cells to infection and promote virus production. We have recently report...

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Detalles Bibliográficos
Autores principales: Gerngross, Lindsey, Lehmicke, Gabrielle, Belkadi, Aghilas, Fischer, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381451/
https://www.ncbi.nlm.nih.gov/pubmed/25886134
http://dx.doi.org/10.1186/s12974-015-0272-1