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PGC-1α modulates denervation-induced mitophagy in skeletal muscle

BACKGROUND: Alterations in skeletal muscle contractile activity necessitate an efficient remodeling mechanism. In particular, mitochondrial turnover is essential for tissue homeostasis during muscle adaptations to chronic use and disuse. While mitochondrial biogenesis appears to be largely governed...

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Detalles Bibliográficos
Autores principales: Vainshtein, Anna, Desjardins, Eric MA, Armani, Andrea, Sandri, Marco, Hood, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381453/
https://www.ncbi.nlm.nih.gov/pubmed/25834726
http://dx.doi.org/10.1186/s13395-015-0033-y