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PGC-1α modulates denervation-induced mitophagy in skeletal muscle
BACKGROUND: Alterations in skeletal muscle contractile activity necessitate an efficient remodeling mechanism. In particular, mitochondrial turnover is essential for tissue homeostasis during muscle adaptations to chronic use and disuse. While mitochondrial biogenesis appears to be largely governed...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381453/ https://www.ncbi.nlm.nih.gov/pubmed/25834726 http://dx.doi.org/10.1186/s13395-015-0033-y |