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X-inactivation informs variance-based testing for X-linked association of a quantitative trait

BACKGROUND: The X chromosome plays an important role in human diseases and traits. However, few X-linked associations have been reported in genome-wide association studies, partly due to analytical complications and low statistical power. RESULTS: In this study, we propose tests of X-linked associat...

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Detalles Bibliográficos
Autores principales: Ma, Li, Hoffman, Gabriel, Keinan, Alon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381508/
https://www.ncbi.nlm.nih.gov/pubmed/25880738
http://dx.doi.org/10.1186/s12864-015-1463-y