The role of DNA methylation in directing the functional organization of the cancer epigenome

The holistic role of DNA methylation in the organization of the cancer epigenome is not well understood. Here we perform a comprehensive, high-resolution analysis of chromatin structure to compare the landscapes of HCT116 colon cancer cells and a DNA methylation-deficient derivative. The NOMe-seq ac...

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Detalles Bibliográficos
Autores principales: Lay, Fides D., Liu, Yaping, Kelly, Theresa K., Witt, Heather, Farnham, Peggy J., Jones, Peter A., Berman, Benjamin P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381519/
https://www.ncbi.nlm.nih.gov/pubmed/25747664
http://dx.doi.org/10.1101/gr.183368.114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381519/
https://www.ncbi.nlm.nih.gov/pubmed/25747664
http://dx.doi.org/10.1101/gr.183368.114

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