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A large-scale, in vivo transcription factor screen defines bivalent chromatin as a key property of regulatory factors mediating Drosophila wing development

Transcription factors (TFs) are key regulators of cell fate. The estimated 755 genes that encode DNA binding domain-containing proteins comprise ∼5% of all Drosophila genes. However, the majority has remained uncharacterized so far due to the lack of proper genetic tools. We generated 594 site-direc...

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Detalles Bibliográficos
Autores principales: Schertel, Claus, Albarca, Monica, Rockel-Bauer, Claudia, Kelley, Nicholas W., Bischof, Johannes, Hens, Korneel, van Nimwegen, Erik, Basler, Konrad, Deplancke, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381523/
https://www.ncbi.nlm.nih.gov/pubmed/25568052
http://dx.doi.org/10.1101/gr.181305.114