Evaluation of azacitidine and entinostat as sensitization agents to cytotoxic chemotherapy in preclinical models of non-small cell lung cancer

Recent clinical data in lung cancer suggests that epigenetically targeted therapy may selectively enhance chemotherapeutic sensitivity. There have been few if any studies rigorously evaluating this hypothesized priming effect. Here we describe a series of investigations testing whether epigenetic pr...

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Detalles Bibliográficos
Autores principales: Vendetti, Frank P., Topper, Michael, Huang, Peng, Dobromilskaya, Irina, Easwaran, Hariharan, Wrangle, John, Baylin, Stephen B., Poirier, J. T., Rudin, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381578/
https://www.ncbi.nlm.nih.gov/pubmed/25474141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381578/
https://www.ncbi.nlm.nih.gov/pubmed/25474141

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