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WMJ-S-001, a novel aliphatic hydroxamate derivative, exhibits anti-angiogenic activities via Src-homology-2-domain-containing protein tyrosine phosphatase 1

Angiogenesis, one of the major routes for tumor invasion and metastasis represents a rational target for therapeutic intervention. Recent development in drug discovery has highlighted the diverse biological and pharmacological properties of hydroxamate derivatives. In this study, we characterized th...

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Detalles Bibliográficos
Autores principales: Chang, Yi-Fang, Hsu, Ya-Fen, Chiu, Pei-Ting, Huang, Wei-Jan, Huang, Shiu-Wen, Ou, George, Sheu, Joen-Rong, Hsu, Ming-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381580/
https://www.ncbi.nlm.nih.gov/pubmed/25415226