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Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma

To identify novel tumor suppressor genes that are down-regulated by promoter hypermethylation in head and neck squamous cell carcinoma (HNSCC), genome-wide methylation profiling was performed using a methylated DNA immunoprecipitation (MeDIP) array in HNSCC and normal mucosa tissue samples. Promoter...

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Detalles Bibliográficos
Autores principales: Zhang, Xiao-Yun, Li, Minle, Sun, Kai, Chen, Xiao-Jie, Meng, Jian, Wu, Lifang, Zhang, Ping, Tong, Xuemei, Jiang, Wei-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381581/
https://www.ncbi.nlm.nih.gov/pubmed/25575809