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Decreased expression of GRIM-19 by DNA hypermethylation promotes aerobic glycolysis and cell proliferation in head and neck squamous cell carcinoma
To identify novel tumor suppressor genes that are down-regulated by promoter hypermethylation in head and neck squamous cell carcinoma (HNSCC), genome-wide methylation profiling was performed using a methylated DNA immunoprecipitation (MeDIP) array in HNSCC and normal mucosa tissue samples. Promoter...
Autores principales: | Zhang, Xiao-Yun, Li, Minle, Sun, Kai, Chen, Xiao-Jie, Meng, Jian, Wu, Lifang, Zhang, Ping, Tong, Xuemei, Jiang, Wei-Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381581/ https://www.ncbi.nlm.nih.gov/pubmed/25575809 |
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