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MIG-7 and phosphorylated prohibitin coordinately regulate lung cancer invasion/metastasis

Growth factors and COX-2/PGE2 enhance lung cancer invasion/metastasis via PI3K/Akt and RAS/Raf. Here, we explored their mechanism of action further. We found first that higher levels of migration inducting gene-7 protein (MIG-7) and PHB phosphorylated at threonine 258 (phospho-PHB(T258)) are positiv...

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Detalles Bibliográficos
Autores principales: Ho, Ming-Yi, Liang, Chi-Ming, Liang, Shu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381602/
https://www.ncbi.nlm.nih.gov/pubmed/25575814