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DNA methylation transcriptionally regulates the putative tumor cell growth suppressor ZNF677 in non-small cell lung cancers

In our study, we investigated the role of ZNF677 in non-small cell lung cancers (NSCLC). By comparing ZNF677 expression in primary tumor (TU) and in the majority of cases also of corresponding non-malignant lung tissue (NL) samples from > 1,000 NSCLC patients, we found tumor-specific downregulati...

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Detalles Bibliográficos
Autores principales: Heller, Gerwin, Altenberger, Corinna, Schmid, Bianca, Marhold, Maximilian, Tomasich, Erwin, Ziegler, Barbara, Müllauer, Leonhard, Minichsdorfer, Christoph, Lang, György, End-Pfützenreuter, Adelheid, Döme, Balazs, Arns, Britt-Madeleine, Fong, Kwun M., Wright, Casey M., Yang, Ian A., Klepetko, Walter, Zielinski, Christoph C., Zöchbauer-Müller, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381603/
https://www.ncbi.nlm.nih.gov/pubmed/25504438