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JNK suppression of chemotherapeutic agents-induced ROS confers chemoresistance on pancreatic cancer stem cells

Chemoresistance associated with cancer stem cells (CSCs), which is now being held responsible for the pervasive therapy resistance of pancreatic cancer, poses a major challenge to the successful management of this devastating malignancy. However, the molecular mechanism underlying the marked chemore...

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Detalles Bibliográficos
Autores principales: Suzuki, Shuhei, Okada, Masashi, Shibuya, Keita, Seino, Manabu, Sato, Atsushi, Takeda, Hiroyuki, Seino, Shizuka, Yoshioka, Takashi, Kitanaka, Chifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381607/
https://www.ncbi.nlm.nih.gov/pubmed/25473894