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Self-nanoemulsifying drug delivery systems ameliorate the oral delivery of silymarin in rats with Roux-en-Y gastric bypass surgery

Roux-en-Y gastric bypass (RYGB) is a popular surgery to reduce the body weight of obese patients. Although food intake is restricted by RYGB, drug absorption is also decreased. The purpose of this study was to develop novel self-nanoemulsifying drug delivery systems (SNEDDS) for enhancing the oral d...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Han, Chang, Cheng-Chih, Shih, Tsung-Hsien, Aljuffali, Ibrahim A, Yeh, Ta-Sen, Fang, Jia-You
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381630/
https://www.ncbi.nlm.nih.gov/pubmed/25848259
http://dx.doi.org/10.2147/IJN.S79522