Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena

Patients with schizophrenia often manifest deficits in behavioral flexibility. Non-competitive NMDA receptor antagonists such as MK-801 induce schizophrenia-like symptoms in rodents, including cognitive functions. Despite work exploring flexibility has been done employing behavioral paradigms with s...

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Detalles Bibliográficos
Autores principales: Svoboda, Jan, Stankova, Anna, Entlerova, Marie, Stuchlik, Ales
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381641/
https://www.ncbi.nlm.nih.gov/pubmed/25883558
http://dx.doi.org/10.3389/fnbeh.2015.00075

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381641/
https://www.ncbi.nlm.nih.gov/pubmed/25883558
http://dx.doi.org/10.3389/fnbeh.2015.00075

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