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Acute administration of MK-801 in an animal model of psychosis in rats interferes with cognitively demanding forms of behavioral flexibility on a rotating arena

Patients with schizophrenia often manifest deficits in behavioral flexibility. Non-competitive NMDA receptor antagonists such as MK-801 induce schizophrenia-like symptoms in rodents, including cognitive functions. Despite work exploring flexibility has been done employing behavioral paradigms with s...

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Detalles Bibliográficos
Autores principales:	Svoboda, Jan, Stankova, Anna, Entlerova, Marie, Stuchlik, Ales
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381641/ https://www.ncbi.nlm.nih.gov/pubmed/25883558 http://dx.doi.org/10.3389/fnbeh.2015.00075

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