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Genome rearrangement affects RNA virus adaptability on prostate cancer cells

Gene order is often highly conserved within taxonomic groups, such that organisms with rearranged genomes tend to be less fit than wild type gene orders, and suggesting natural selection favors genome architectures that maximize fitness. But it is unclear whether rearranged genomes hinder adaptabili...

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Detalles Bibliográficos
Autores principales: Pesko, Kendra, Voigt, Emily A., Swick, Adam, Morley, Valerie J., Timm, Collin, Yin, John, Turner, Paul E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381649/
https://www.ncbi.nlm.nih.gov/pubmed/25883601
http://dx.doi.org/10.3389/fgene.2015.00121