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Novel Primary Immunodeficiency Candidate Genes Predicted by the Human Gene Connectome
Germline genetic mutations underlie various primary immunodeficiency (PID) diseases. Patients with rare PID diseases (like most non-PID patients and healthy individuals) carry, on average, 20,000 rare and common coding variants detected by high-throughput sequencing. It is thus a major challenge to...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381650/ https://www.ncbi.nlm.nih.gov/pubmed/25883595 http://dx.doi.org/10.3389/fimmu.2015.00142 |