Caspase Activation and Aberrant Cell Growth in a p53(+/+) Cell Line from a Li-Fraumeni Syndrome Family

Wild-type p53 is well known to induce cell cycle arrest and apoptosis to block aberrant cell growth. However, p53's unique role in apoptosis and cell proliferation in Li-Fraumeni Syndrome (LFS) has not been well elucidated. The aim of this study is to characterize the activity of wild-type p53...

Descripción completa

Detalles Bibliográficos
Autor principal: Sherif, Zaki A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381654/
https://www.ncbi.nlm.nih.gov/pubmed/25866679
http://dx.doi.org/10.1155/2015/789201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381654/
https://www.ncbi.nlm.nih.gov/pubmed/25866679
http://dx.doi.org/10.1155/2015/789201

Ejemplares similares