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Two preclinical tests to evaluate anticancer activity and to help validate drug candidates for clinical trials

Current approaches to assessing preclinical anticancer activity do not reliably predict drug efficacy in cancer patients. Most of the compounds that show remarkable anticancer effects in preclinical models actually fail when tested in clinical trials. We blame these failures on the complexity of the...

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Detalles Bibliográficos
Autor principal: López-Lázaro, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381701/
https://www.ncbi.nlm.nih.gov/pubmed/25859551