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Dynamic recruitment of the curvature-sensitive protein ArhGAP44 to nanoscale membrane deformations limits exploratory filopodia initiation in neurons

In the vertebrate central nervous system, exploratory filopodia transiently form on dendritic branches to sample the neuronal environment and initiate new trans-neuronal contacts. While much is known about the molecules that control filopodia extension and subsequent maturation into functional synap...

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Detalles Bibliográficos
Autores principales: Galic, Milos, Tsai, Feng-Chiao, Collins, Sean R, Matis, Maja, Bandara, Samuel, Meyer, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381785/
https://www.ncbi.nlm.nih.gov/pubmed/25498153
http://dx.doi.org/10.7554/eLife.03116