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Development of sample clean up methods for the analysis of Mycobacterium tuberculosis methyl mycocerosate biomarkers in sputum extracts by gas chromatography–mass spectrometry

A proof of principle gas chromatography–mass spectrometry method is presented, in combination with clean up assays, aiming to improve the analysis of methyl mycocerosate tuberculosis biomarkers from sputum. Methyl mycocerosates are generated from the transesterification of phthiocerol dimycocerosate...

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Detalles Bibliográficos
Autores principales: Nicoara, Simona C., Turner, Nicholas W., Minnikin, David E., Lee, Oona Y.-C., O'Sullivan, Denise M., McNerney, Ruth, Mutetwa, Reggie, Corbett, Liz E., Morgan, Geraint H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381843/
https://www.ncbi.nlm.nih.gov/pubmed/25728371
http://dx.doi.org/10.1016/j.jchromb.2015.02.010