Expanding antitumor therapeutic windows by targeting cancer-specific nicotinamide adenine dinucleotide phosphate-biogenesis pathways

Nicotinamide adenine dinucleotide phosphate (NADPH) biogenesis is an essential mechanism by which both normal and cancer cells maintain redox balance. While antitumor approaches to treat cancers through elevated reactive oxygen species (ROS) are not new ideas, depleting specific NADPH-biogenesis pat...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Gaurab, Gerber, David E, Boothman, David A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381889/
https://www.ncbi.nlm.nih.gov/pubmed/25870517
http://dx.doi.org/10.2147/CPAA.S79760

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381889/
https://www.ncbi.nlm.nih.gov/pubmed/25870517
http://dx.doi.org/10.2147/CPAA.S79760

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