Cargando…

Expanding antitumor therapeutic windows by targeting cancer-specific nicotinamide adenine dinucleotide phosphate-biogenesis pathways

Nicotinamide adenine dinucleotide phosphate (NADPH) biogenesis is an essential mechanism by which both normal and cancer cells maintain redox balance. While antitumor approaches to treat cancers through elevated reactive oxygen species (ROS) are not new ideas, depleting specific NADPH-biogenesis pat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chakrabarti, Gaurab, Gerber, David E, Boothman, David A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381889/ https://www.ncbi.nlm.nih.gov/pubmed/25870517 http://dx.doi.org/10.2147/CPAA.S79760

Ejemplares similares

Nicotinamide adenine dinucleotide as a photocatalyst
por: Kim, Jinhyun, et al.
Publicado: (2019)

The Role of Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Lung Architecture Remodeling
por: Harijith, Anantha, et al.
Publicado: (2017)

carba Nicotinamide Adenine Dinucleotide Phosphate: Robust Cofactor for Redox Biocatalysis
por: Zachos, Ioannis, et al.
Publicado: (2021)

Advances in the study of nicotinamide adenine dinucleotide phosphate oxidase in myocardial remodeling
por: Miao, Runran, et al.
Publicado: (2022)

Roles of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase in Angiogenesis: Isoform-Specific Effects
por: Wang, Haibo, et al.
Publicado: (2017)

Metabolism and biochemical properties of nicotinamide adenine dinucleotide (NAD) analogs, nicotinamide guanine dinucleotide (NGD) and nicotinamide hypoxanthine dinucleotide (NHD)
por: Yaku, Keisuke, et al.
Publicado: (2019)

Nicotinamide Adenine Dinucleotide Phosphate Oxidases Are Everywhere in Brain Disease, but Not in Huntington’s Disease?
por: Villegas, Luisana, et al.
Publicado: (2021)

Bipyridines mediate electron transfer from an electrode to nicotinamide adenine dinucleotide phosphate
por: Wayama, Fumiya, et al.
Publicado: (2022)

Nicotinamide adenine dinucleotide is transported into mammalian mitochondria
por: Davila, Antonio, et al.
Publicado: (2018)

Nicotinamide adenine dinucleotide phosphate oxidase activation and neuronal death after ischemic stroke
por: Shen, Jiamei, et al.
Publicado: (2019)

Analyzing Nicotinamide Adenine Dinucleotide Phosphate Oxidase Activation in Aging and Vascular Amyloid Pathology
por: Radbruch, Helena, et al.
Publicado: (2017)

Neuromeric Distribution of Nicotinamide Adenine Dinucleotide Phosphate-Diaphorase Activity in the Adult Lamprey Brain
por: Pombal, Manuel A., et al.
Publicado: (2022)

Nicotinamide adenine dinucleotide suppresses epileptogenesis at an early stage
por: Liu, Juan, et al.
Publicado: (2017)

Pharmacology and Potential Implications of Nicotinamide Adenine Dinucleotide Precursors
por: She, Jing, et al.
Publicado: (2021)

Editorial: The Versatile Role of Nicotinamide Adenine Dinucleotide in Immunity
por: Rissiek, Björn, et al.
Publicado: (2021)

Three variants in the nicotinamide adenine dinucleotide phosphate oxidase complex are associated with HCV‐related liver damage
por: Page, Sandra J., et al.
Publicado: (2017)

Nicotinamide Adenine Dinucleotide Phosphate Oxidases in Glucose Homeostasis and Diabetes-Related Endothelial Cell Dysfunction
por: Brown, Oliver Ian, et al.
Publicado: (2021)

Pathways Linking Nicotinamide Adenine Dinucleotide Phosphate Production to Endoplasmic Reticulum Protein Oxidation and Stress
por: Gansemer, Erica R., et al.
Publicado: (2022)

Semisynthetic biosensors for mapping cellular concentrations of nicotinamide adenine dinucleotides
por: Sallin, Olivier, et al.
Publicado: (2018)

Nicotinamide adenine dinucleotide and the sirtuins caution: Pro‐cancer functions
por: Palmer, Raymond D., et al.
Publicado: (2021)

Nicotinamide adenine dinucleotide metabolism in the immune response, autoimmunity and inflammageing
por: Navarro, Maria N., et al.
Publicado: (2021)

Improved Yield for the Enzymatic Synthesis of Radiolabeled Nicotinamide Adenine Dinucleotide
por: Eller, Jared, et al.
Publicado: (2023)

Oral Administration of Nicotinamide Mononucleotide Increases Nicotinamide Adenine Dinucleotide Level in an Animal Brain
por: Ramanathan, Chidambaram, et al.
Publicado: (2022)

pH-Dependent Flavin Adenine Dinucleotide and Nicotinamide Adenine Dinucleotide Ultraviolet Resonance Raman (UVRR) Spectra at Intracellular Concentration
por: Merk, Virginia, et al.
Publicado: (2021)

The effects of nicotinamide adenine dinucleotide in cardiovascular diseases: Molecular mechanisms, roles and therapeutic potential
por: Zhang, Xiaokai, et al.
Publicado: (2021)

Implication of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase and Its Inhibitors in Alzheimer’s Disease Murine Models
por: Fragoso-Morales, Leticia Guadalupe, et al.
Publicado: (2021)

Glutamic-oxaloacetic transaminase 1 regulates adipocyte differentiation by altering nicotinamide adenine dinucleotide phosphate content
por: Yang, Yang, et al.
Publicado: (2022)

The Effects of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase and Erythropoietin, and Their Interactions in Angiogenesis: Implications in Retinopathy of Prematurity
por: Cung, Thaonhi, et al.
Publicado: (2022)

Nicotinamide adenine dinucleotide replenishment rescues colon degeneration in aged mice
por: Zhu, Xudong, et al.
Publicado: (2017)

Exogenous Nicotinamide Adenine Dinucleotide Induces Resistance to Citrus Canker in Citrus
por: Alferez, Fernando M., et al.
Publicado: (2018)

Impaired Nicotinamide Adenine Dinucleotide Biosynthesis in the Kidney of Chronic Kidney Disease
por: Liu, Xinhui, et al.
Publicado: (2021)

Nicotinamide Adenine Dinucleotide (NAD) Metabolism as a Relevant Target in Cancer
por: Navas, Lola E., et al.
Publicado: (2022)

Nicotinamide Adenine Dinucleotide Precursor Suppresses Hepatocellular Cancer Progression in Mice
por: Pang, Nengzhi, et al.
Publicado: (2023)

Future Perspectives for the Identification and Sequencing of Nicotinamide Adenine Dinucleotide-Capped RNAs
por: Möhler, Marvin, et al.
Publicado: (2023)

A Model of Interaction between Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase and Apocynin Analogues by Docking Method
por: Jiang, Jie, et al.
Publicado: (2013)

Spectroscopy and Speciation Studies on the Interactions of Aluminum (III) with Ciprofloxacin and β-Nicotinamide Adenine Dinucleotide Phosphate in Aqueous Solutions
por: Ma, Xiaoling, et al.
Publicado: (2012)

The effect of nicotinamide adenine dinucleotide phosphate oxidase 4 on migration and invasion of fibroblast-like synoviocytes in rheumatoid arthritis
por: Lee, Ha-Reum, et al.
Publicado: (2020)

The Roles of Nicotinamide Adenine Dinucleotide Phosphate Reoxidation and Ammonium Assimilation in the Secretion of Amino Acids as Byproducts of Clostridium thermocellum
por: Yayo, Johannes, et al.
Publicado: (2023)

The senotherapeutic nicotinamide riboside raises platelet nicotinamide adenine dinucleotide levels but cannot prevent storage lesion
por: Delabie, Willem, et al.
Publicado: (2019)

Precursor comparisons for the upregulation of nicotinamide adenine dinucleotide. Novel approaches for better aging
por: Palmer, Raymond D., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_25qsncpddb5vhbmt4q9irmc066