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PPARγ induces growth inhibition and apoptosis through upregulation of insulin-like growth factor-binding protein-3 in gastric cancer cells

Peroxisome proliferator activator receptor-gamma (PPARγ) is a ligand-activated transcriptional factor involved in the carcinogenesis of various cancers. Insulin-like growth factor-binding protein-3 (IGFBP-3) is a tumor suppressor gene that has anti-apoptotic activity. The purpose of this study was t...

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Detalles Bibliográficos
Autores principales: Kim, S.Y., Kim, M.S., Lee, M.K., Kim, J.S., Yi, H.K., Nam, S.Y., Lee, D.Y., Hwang, P.H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381942/
https://www.ncbi.nlm.nih.gov/pubmed/25590353
http://dx.doi.org/10.1590/1414-431X20144212