Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway

This study investigated the in vitro and in vivo antiproliferative activity of esculetin against hepatocellular carcinoma, and clarified its potential molecular mechanisms. Cell viability was determined by the MTT (tetrazolium) colorimetric assay. In vivo antitumor activity of esculetin was evaluate...

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Detalles Bibliográficos
Autores principales: Wang, J., Lu, M.L., Dai, H.L., Zhang, S.P., Wang, H.X., Wei, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação Brasileira de Divulgação Científica 2014
Materias:
Biomedical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381945/
https://www.ncbi.nlm.nih.gov/pubmed/25517918
http://dx.doi.org/10.1590/1414-431X20144074

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381945/
https://www.ncbi.nlm.nih.gov/pubmed/25517918
http://dx.doi.org/10.1590/1414-431X20144074

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