NADPH Oxidase 4-Derived H(2)O(2) Promotes Aberrant Retinal Neovascularization via Activation of VEGF Receptor 2 Pathway in Oxygen-Induced Retinopathy

NADPH oxidase 4 (Nox4) is a major isoform of NADPH oxidase in retinal endothelial cells. Our previous study suggests that upregulation of Nox4 in retinal endothelial cells contributes to retinal vascular leakage in diabetes. In the current study, we investigated the role and mechanism of Nox4 in reg...

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Detalles Bibliográficos
Autores principales: Li, Jingming, Wang, Joshua J., Zhang, Sarah X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381975/
https://www.ncbi.nlm.nih.gov/pubmed/25866826
http://dx.doi.org/10.1155/2015/963289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381975/
https://www.ncbi.nlm.nih.gov/pubmed/25866826
http://dx.doi.org/10.1155/2015/963289

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