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Gambogic Acid Lysinate Induces Apoptosis in Breast Cancer MCF-7 Cells by Increasing Reactive Oxygen Species

Gambogic acid (GA) inhibits the proliferation of various human cancer cells. However, because of its water insolubility, the antitumor efficacy of GA is limited. Objectives. To investigate the antitumor activity of gambogic acid lysinate (GAL) and its mechanism. Methods. Inhibition of cell prolifera...

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Detalles Bibliográficos
Autores principales: Zhen, Yong-Zhan, Lin, Ya-Jun, Li, Kai-Ji, Yang, Xiao-Shan, Zhao, Yu-Fang, Wei, Jie, Wei, Jing-Bo, Hu, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4381976/
https://www.ncbi.nlm.nih.gov/pubmed/25866542
http://dx.doi.org/10.1155/2015/842091