Adding Vitamin E-TPGS to the Formulation of Genexol-PM: Specially Mixed Micelles Improve Drug-Loading Ability and Cytotoxicity against Multidrug-Resistant Tumors Significantly

Genexol-PM, produced by Samyang Company (Korea) is an excellent preparation of paclitaxel (PTX) for clinical cancer treatment. However, it cannot resolve the issue of multidrug resistance (MDR)—a significant problem in the administration of PTX to cancer patients. To increase the efficacy of Genexol...

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Detalles Bibliográficos
Autores principales: Fan, Zhuoyang, Chen, Cheng, Pang, Xiaoying, Yu, Zhou, Qi, Yang, Chen, Xinyi, Liang, Huihui, Fang, Xiaoling, Sha, Xianyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382049/
https://www.ncbi.nlm.nih.gov/pubmed/25831130
http://dx.doi.org/10.1371/journal.pone.0120129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382049/
https://www.ncbi.nlm.nih.gov/pubmed/25831130
http://dx.doi.org/10.1371/journal.pone.0120129

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