Propofol Causes Vasodilation In Vivo via TRPA1 Ion Channels: Role of Nitric Oxide and BK(Ca) Channels

BACKGROUND: Transient receptor potential (TRP) ion channels of the A1 (TRPA1) and V1 (TRPV1) subtypes are key regulators of vasomotor tone. Propofol is an intravenous anesthetic known to cause vasorelaxation. Our objectives were to examine the extent to which TRPA1 and/or TRPV1 ion channels mediate...

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Detalles Bibliográficos
Autores principales: Sinha, Sayantani, Sinharoy, Pritam, Bratz, Ian N., Damron, Derek S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382130/
https://www.ncbi.nlm.nih.gov/pubmed/25830814
http://dx.doi.org/10.1371/journal.pone.0122189

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382130/
https://www.ncbi.nlm.nih.gov/pubmed/25830814
http://dx.doi.org/10.1371/journal.pone.0122189

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