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Propofol Causes Vasodilation In Vivo via TRPA1 Ion Channels: Role of Nitric Oxide and BK(Ca) Channels
BACKGROUND: Transient receptor potential (TRP) ion channels of the A1 (TRPA1) and V1 (TRPV1) subtypes are key regulators of vasomotor tone. Propofol is an intravenous anesthetic known to cause vasorelaxation. Our objectives were to examine the extent to which TRPA1 and/or TRPV1 ion channels mediate...
Autores principales: | Sinha, Sayantani, Sinharoy, Pritam, Bratz, Ian N., Damron, Derek S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4382130/ https://www.ncbi.nlm.nih.gov/pubmed/25830814 http://dx.doi.org/10.1371/journal.pone.0122189 |
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